The Stuyvesant High School Online Course Guide


Genetics Research SB3PGR

The student goals of this one-term course are to:

Explore the study of heredity across species
Become proficient in the practice and interpretation of classical genetic analysis
Connect classical genetic studies with modern genomic approaches

The Central Question: What's up with DNA? Some history -

Genetics was initially a study of traits that are passed from generation to generation.
Farmers and breeders were really the first geneticists. Why do you think so?
Mendel's studies led to a curiosity about the basis for inheritance.
Modern genetic analysis emerged years later with Morgan's studies of flies.
Modern understanding of gene expression emerged with Jacob and Monod's work.
The Human Genome project promises to identify the genetic basis for many diseases.

How we will study this subject:

Classroom Instruction

Classical analysis techniques: Punnett squares, Probabilities
Chromosomes and heredity I: Linkage and Epistasis
Chromosomes and heredity II: Genetic Diseases, Pedigrees
Molecular basis of heredity: DNA and Gene expression, The Central Dogma
Human Genomics: Approaches and Implications, Ethics
Laboratory Studies/Field work: Trip To DNA Learning Center West at Cold Spring Harbor
Individual students will analyze their own DNA on a one-day trip to CSH!
Lab reports will involve analysis of student data and use of NIH databases.

Prerequisites: Successful completion of SL1 and SL2 or equivalents, Biology/LE Regents Proficiency. SB3PGR is open to sophomores, juniors and seniors in the fall term only.

Fulfillment of Requirements: SB3PGR is a prerequisite and/or co-requisite for A.P. Biology.

Grading Policy and Assessments: 70% Exams including cumulative final, 20% Lab reports and Homework assignments, 10% Daily oral class participation and In-class assessments.



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